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B+ | Fighting Childhood Cancer B+ | Fighting Childhood Cancer
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Androgen activity in the normal male embryonic hindbrain drives lethal PFA ependymoma
South, Texas Julia Travagline 11/20/24 South, Texas Julia Travagline 11/20/24

Androgen activity in the normal male embryonic hindbrain drives lethal PFA ependymoma

Androgen activity in the normal male embryonic hindbrain drives lethal PFA ependymoma

Dr. Jiao Zhang, Ph.D. – Baylor College of Medicine, Houston TX

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HBEGF as a novel therapeutic target for Diffuse Midline Glioma
Northeast, New York Julia Travagline 11/20/24 Northeast, New York Julia Travagline 11/20/24

HBEGF as a novel therapeutic target for Diffuse Midline Glioma

HBEGF as a novel therapeutic target for Diffuse Midline Glioma

Dr. Oren Becher, M.D. – Icahn School of Medicine at Mount Sinai, New York, NY

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Therapeutic targeting of CDK12/13 and PARP in H3G34RN mutant pediatric glioma
South, Texas Julia Travagline 11/20/24 South, Texas Julia Travagline 11/20/24

Therapeutic targeting of CDK12/13 and PARP in H3G34RN mutant pediatric glioma

Therapeutic targeting of CDK12/13 and PARP in H3G34RN mutant pediatric glioma

Dr. Jamie Anastas, Ph.D. – Baylor College of Medicine, Houston, TX

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Preclinical evaluation of omacetaxine as a novel therapeutic for ATRT
Midwest, Michigan Julia Travagline 11/20/24 Midwest, Michigan Julia Travagline 11/20/24

Preclinical evaluation of omacetaxine as a novel therapeutic for ATRT

Preclinical evaluation of omacetaxine as a novel therapeutic for ATRT

Dr. John Prensner, M.D., Ph.D. – University of Michigan Medical Center (Michigan Medicine), Ann Arbor, MI

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Developing Human Cerebellar Organoid Models of Group 4 Medulloblastoma to Identify the Cell of Origin and Mechanisms that Support Oncogenesis
Northeast, Washington D.C. Julia Travagline 11/20/24 Northeast, Washington D.C. Julia Travagline 11/20/24

Developing Human Cerebellar Organoid Models of Group 4 Medulloblastoma to Identify the Cell of Origin and Mechanisms that Support Oncogenesis

Developing Human Cerebellar Organoid Models of Group 4 Medulloblastoma to Identify the Cell of Origin and Mechanisms that Support Oncogenesis

Dr. Yanxin Pei, M.D. – Children's Research Institute (CNMC), Washington, D.C.

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Brain Network Organization and Long-Term Cognitive Outcome in Pediatric Brain Tumor Patients
Midwest, Missouri Julia Travagline 11/22/23 Midwest, Missouri Julia Travagline 11/22/23

Brain Network Organization and Long-Term Cognitive Outcome in Pediatric Brain Tumor Patients

Brain Network Organization and Long-Term Cognitive Outcome in Pediatric Brain Tumor Patients

Dr. Stephanie Perkins – Washington University in St. Louis, St Louis, MO

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Dual-label optical genome mapping for the identification of novel co-occurring genetic and epigenetic alterations in diffuse midline gliomas
Northeast Julia Travagline 11/22/23 Northeast Julia Travagline 11/22/23

Dual-label optical genome mapping for the identification of novel co-occurring genetic and epigenetic alterations in diffuse midline gliomas

Dual-label optical genome mapping for the identification of novel co-occurring genetic and epigenetic alterations in diffuse midline gliomas

Dr. Miriam Bornhorst – Children's National Health System Department of Neurology, Washington D.C.

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Preclinical evaluation of BRD inhibitors to treat Posterior Fossa A ependymoma
Northeast, New York Julia Travagline 11/22/23 Northeast, New York Julia Travagline 11/22/23

Preclinical evaluation of BRD inhibitors to treat Posterior Fossa A ependymoma

Preclinical evaluation of BRD inhibitors to treat Posterior Fossa A ependymoma

Dr. Oren Becher – Icahn School of Medicine at Mount Sinai, New York, NY

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Epigenetic targeting of radiation resistant medulloblastoma
Northeast, Maryland Julia Travagline 12/14/22 Northeast, Maryland Julia Travagline 12/14/22

Epigenetic targeting of radiation resistant medulloblastoma

Epigenetic targeting of radiation resistant medulloblastoma

Johns Hopkins University, Baltimore, MD

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Enhancement of Oncolytic Virotherapy with Directed Drug Delivery for Pediatric Brain Tumors
South, Alabama Julia Travagline 12/14/22 South, Alabama Julia Travagline 12/14/22

Enhancement of Oncolytic Virotherapy with Directed Drug Delivery for Pediatric Brain Tumors

Enhancement of Oncolytic Virotherapy with Directed Drug Delivery for Pediatric Brain Tumors

MD Anderson Cancer Center, Houston, TX

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PTEFb-dependent transcriptional reorganization in the glioma adaptive response to radiotherapy
West, Colorado Julia Travagline 12/14/22 West, Colorado Julia Travagline 12/14/22

PTEFb-dependent transcriptional reorganization in the glioma adaptive response to radiotherapy

PTEFb-dependent transcriptional reorganization in the glioma adaptive response to radiotherapy

University of Colorado Denver, AMC and DC, Aurora, CO

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Exploiting NAD Metabolism Defects in Pediatric Brain Tumors
Northeast, Connecticut Julia Travagline 12/8/21 Northeast, Connecticut Julia Travagline 12/8/21

Exploiting NAD Metabolism Defects in Pediatric Brain Tumors

Exploiting NAD Metabolism Defects in Pediatric Brain Tumors

Yale University, New Haven, CT

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Stimulating Macrophages to Eat Pediatric Brain Cancer: Combining Anti-CD47 and Irradiation to Enhance the Treatment of Group 3 Medulloblastoma
Utah, West Julia Travagline 8/10/21 Utah, West Julia Travagline 8/10/21

Stimulating Macrophages to Eat Pediatric Brain Cancer: Combining Anti-CD47 and Irradiation to Enhance the Treatment of Group 3 Medulloblastoma

Stimulating Macrophages to Eat Pediatric Brain Cancer: Combining Anti-CD47 and Irradiation to Enhance the Treatment of Group 3 Medulloblastoma

University of Utah, Salt Lake City, UT

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Overcoming Resistance of CAR T Cells Immunotherapy with CBP/ß-catenin Antagonists in Pediatric Glioma and Ependymoma
California, West Julia Travagline 8/10/21 California, West Julia Travagline 8/10/21

Overcoming Resistance of CAR T Cells Immunotherapy with CBP/ß-catenin Antagonists in Pediatric Glioma and Ependymoma

Overcoming Resistance of CAR T Cells Immunotherapy with CBP/ß-catenin Antagonists in Pediatric Glioma and Ependymoma

Beckman Research Institute of the City of Hope, Duarte, CA

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Boosting Immunovirotherapy with Tumor Vaccination to Treat Pediatric Malignant Brain Tumors
Alabama, South Julia Travagline 8/10/21 Alabama, South Julia Travagline 8/10/21

Boosting Immunovirotherapy with Tumor Vaccination to Treat Pediatric Malignant Brain Tumors

Boosting Immunovirotherapy with Tumor Vaccination to Treat Pediatric Malignant Brain Tumors

University of Alabama at Birmingham, Birmingham, AL

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A Novel Approach to Target ACVR1 as a Treatment to Pediatric Cancer
Georgia, South Julia Travagline 8/10/21 Georgia, South Julia Travagline 8/10/21

A Novel Approach to Target ACVR1 as a Treatment to Pediatric Cancer

A Novel Approach to Target ACVR1 as a Treatment to Pediatric Cancer

Georgia Tech Research Corporation, Atlanta, GA

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Overcoming Innate Immune Evasion in Pediatric High Grade Glioma
Colorado, West Julia Travagline 8/10/21 Colorado, West Julia Travagline 8/10/21

Overcoming Innate Immune Evasion in Pediatric High Grade Glioma

Overcoming Innate Immune Evasion in Pediatric High Grade Glioma

University of Colorado Denver, AMC and DC, Aurora, CO

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Targeting MEK and CDK4/6 in DIPG
Illinois, Midwest Julia Travagline 8/9/21 Illinois, Midwest Julia Travagline 8/9/21

Targeting MEK and CDK4/6 in DIPG

Targeting MEK and CDK4/6 in DIPG

Lurie Children’s Hospital, Chicago, IL

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Improving Brain Tumor Targeted Antigen Receptor T Cell Function
California, West Julia Travagline 8/9/21 California, West Julia Travagline 8/9/21

Improving Brain Tumor Targeted Antigen Receptor T Cell Function

Improving Brain Tumor Targeted Antigen Receptor T Cell Function

City of Hope, Duarte, CA

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In-Vivo Organogenesis Approach to Elucidate Drivers of Medulloblastoma Development and Identify Therapeutic Targets
California, West Julia Travagline 8/9/21 California, West Julia Travagline 8/9/21

In-Vivo Organogenesis Approach to Elucidate Drivers of Medulloblastoma Development and Identify Therapeutic Targets

In-Vivo Organogenesis Approach to Elucidate Drivers of Medulloblastoma Development and Identify Therapeutic Targets

University of California, San Francisco, CA

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